Vicore obtains SARS coronavirus patent for C21 in the USA
“COVID-19 may be just a few mutations away from evading existing vaccines, and we know that even vaccinated people can both pass on the infection and become ill themselves” said Carl-Johan Dalsgaard, CEO of Vicore Pharma. “This C21/CoV patent gives Vicore patent protection in the US market until December 2040.”
A major clinical impact of C21 on respiratory function in COVID-19 was documented in a recent phase 2 trial showing that C21 reduced the need for supplemental oxygen in hospitalized patients by 90%. An ongoing international pivotal phase 3 study (ATTRACT-3) involving around 600 COVID-19 patients is expected to deliver top-line data in H1 2022.
“The use of C21 to promote accelerated resolution of lung damage by SARS-CoV-2 and related conronaviruses is a promising and innovative therapeutic approach” said Johan Raud, CSO of Vicore. “Vicore is also presently pursuing equivalent protection for this innovation outside the US.”
C21 – a first-in-class AT2R agonist
C21 is a first-in-class, orally available, low molecular weight, angiotensin II type 2 receptor (AT2R) agonist that activates the “protective arm” of the renin-angiotensin system (RAS) leading to resolution and regeneration following tissue damage. The compound is currently in a phase 2 proof-of-concept trial in IPF and in a pivotal phase 3 trial in COVID-19. Given the therapeutic potential of AT2R agonism in additional indications with significant unmet medical needs, Vicore has intensified the efforts to develop proprietary follow-up molecules with differentiated profiles.
For further information, please contact:
Carl-Johan Dalsgaard, CEO
Phone: +46 70 975 98 63
This information was submitted for publication on September 22, 2021 at 08.00 CET.