Unlocking the potential of a new class of drugs-Angiotensin II Type 2 Receptor Agonists (ATRAGs)

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Webinar - Final phase 2a AIR trial results with buloxibutid in IPF

Financial reports

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Who we are

Vicore is an innovative clinical-stage biopharmaceutical company dedicated to creating life- changing treatments in diseases where the AT2 (angiotensin II type 2) receptor has a central role in stopping and reversing disease pathology.

We have a strong history of collaboration with the scientific community, which has led to a wealth of preclinical data and ongoing clinical research in multiple indications to prove the AT2 receptor biology. Embedded in our approach is the determination to find holistic solutions for patients and their families.

Mechanism of Action

In IPF, the novel and multimodal mechanism of action of buloxibutid targets the underlying fibrosis by stimulating the protective arm of the renin-angiotensin system (RAS). Consequently, there is an upstream effect in terms of promoting alveolar repair and maintenance of alveolar integrity thereby reducing fibrosis formation, stabilizing disease, and increasing lung capacity.

Read more about the broad therapeutic potential of AT2 receptor activation.

What we do

Vicore Pharma is a clinical-stage biopharmaceutical company unlocking the potential of a new class of drugs with disease-modifying potential in respiratory and fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). The company’s lead program, buloxibutid, is a first-in-class oral small molecule angiotensin II type 2 receptor agonist, which has received Orphan Drug and Fast Track designation from the United States Food and Drug Administration and is currently being investigated in the global 52-week Phase 2b ASPIRE trial in IPF.

Vicore is publicly listed on the Nasdaq Stockholm exchange with the ticker VICO.

 

Now enrolling:

The ASPIRE IPF Phase 2b trial of buloxibutid

in adults with idiopathic pulmonary fibrosis (IPF)

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