About Us

In brief

Vicore Pharma is a biotech company focused on helping patients who suffer from rare diseases where there is currently no satisfactory treatment. Our focus is on the development of orphan drugs in fibrotic diseases.

Vicore Pharma has designed, synthesized and patented a unique collection of small, non-peptide molecules that stimulate the AT2 receptor within the Renin Angiotensin System (RAS). The RAS plays a critical role in maintaining blood pressure, as well as fluid and salt balance. The molecules could potentially be developed into a clinically important and commercially attractive new class of drugs.

The lead candidate drug, “Compound 21” (“C21”) was selected from a large number of patent-protected compounds. It is well-suited for both oral and intravenous administration.

Phase I studies has been performed and a Phase IIa study for the lead indication Idiopathic Pulmonary Fibrosis (IPF) is estimated to start during Q1 2018.

Vision

Vicore Pharma´s vision is to lead the development of new molecules with agonistic action to the AT2 receptor into successful drug entities, helping serious disease sufferers to better health.

Strategy

  • To develop candidate drug molecules, based on the proven AT2 receptor agonism platform through safety and clinical stages, into clinical drug entities for human acute and chronic use.
  • To prioritize the clinical development of C21 within idiopathic pulmonary fibrosis (IPF)
  • Identify and develop a second fibrosis indication within the orphan drug area
  • To enter into collaboration and licensing agreements with pharmaceutical companies to maximize development opportunities of company assets in harmony with company business objectives.

Background

Vicore Pharma AB was founded in 2000 based on explorative research at Uppsala University and Sahlgrenska Academy at Gothenburg University. In the early years Vicore Pharma was financed by venture capital companies, but in 2003 the ownership returned to the original founders. In 2007  Vita Nova Ventures acquired all shares in Vicore Pharma AB from the founders. In 2009 Mintage Scientific (now Vicore Pharma Holding) acquired all the shares in Vicore Pharma AB and 34% of the shares in I-Tech AB. Vicore Pharma Holding has completed eight share issues which together have brought in approx. 131 million SEK.

Management

Per Jansson

Per Jansson, D.D.S.
Managing Director

 Per has held leading positions in the medical industry for more than twenty years. He has managed and successfully grown research-based start-up companies, both clinically and commercially.

Johanna Gräns

Johanna Gräns, Ph.D
Regulatory Affairs Manager

Johanna has a Ph.D and expertise in pharmaceutical metabolism. She has extensive experience in preclinical interpretation and is responsible for producing and refining the regulatory documentation for C21.

Dan Isaksson

Dan Isaksson, Ph.D
Senior R&D Chemist

Dan is an organic chemist and has been working in the biotech industry since 2009.  A lot of the R&D work has been around formulation and controlled release of actives from various matrixes, as well as patenting promising new technologies.

Ulrike Steckelings

Ulrike Muscha Steckelings M.D., Ph.D. and Professor in Pharmacology
CSO

Muscha has extensive research experience in the fields of the Renin Angiotensin System and the AT2 receptor, and has published numerous articles in peer reviewed journals. She also holds a clinical degree in dermatology. Muscha is a Professor of Integrative Pharmacology at University of Southern Denmark, Odense, in parallel with her role at Vicore Pharma.

 

Hans Jeppsson, Ph.D., Finance
CFO

Hans is a Finance professional with cross-disciplinary background in Finance and Medicine in both academic and industry settings. Several years of research and biologics to equity research analyst at Danske Bank and post-doc research at UC Berkeley. Hans works part-time as Assistant Professor in Finance at Gothenburg School of Economics and Law.

Kicki Johansson, Ph.D. Pharm
Head of Drug Development

Kicki has been responsible for the development of more than 40 new compounds in different disease areas within Astra Zeneca. Most recently she has had a position as Senior Project Leader/VP for the clinical development of oral anti-inflammatory projects within the Respiratory and Inflammatory Disease Division of AstraZeneca.

Nina Carlén

Nina Carlén
IR, Communication & Administration

Nina has more than 15 years’ experience of working with marketing and communication in the medical industry.

Board of Directors

Leif Darner
Chairman

Leif is the owner of consulting firm Darner Asset Management AB. Prior to this, he was an Executive Director on the Board of Management at AkzoNobel, where he was responsible for Performance Coatings from 2008 and for Chemicals from 2004.

Other assignments: Board member at LKAB AB, Sweden, Flowserve Corporation, Dallas, US and I-Tech AB.

 

Kjell Stenberg
Board member

Kjell has extensive board experience in a large number of companies that are active across a range of industries.

Other assignments: Board member of WntResearch AB, Kjell Stenberg AB and CN Stenberg AB.

 

Peter Ström

Peter Ström
Board Member

Peter Ström has an MBA from the Stockholm School of Economics. He has held senior positions at companies including KabiPharmacia UK (CEO) and IMSHealth Europe (VP).

Other assignments: Chairman of WntResearch AB. Board member of Stockholm Corporate Finance AB, Dentosystem Scandinavia AB. Deputy board member of Comtax Support Limited.

Göran Wessman

Göran Wessman
Board member

Göran has over twenty years’ experience in management positions in pharmaceutical and medical device companies, as well as from the CRO business area of clinical research. Göran has held senior leadership positions at Nobel Biocare, Boule Group and Carmel Pharma.

Other assignments: Board member of ITIN Holding AB (publ), Vicore Pharma AB, Protem Wessman AB and Protem Företagsförvaltning AB.

Jacob Gunterberg
Board member

Partner with HealthCap since 2007. Prior to joining HealthCap, he worked with investment banking at ABB Aros Securities where he was Director and responsible for the life sciences sector as well as with Hjalmarsson & Gunterberg Corporate Finance which he co-founded in 2000.
Other board assignments: Carisma Therapeutics, Inc, USA and Trimb Holding AB, Sweden.

 

 

Hans Schikan
Board member

Hans brings more than 25 years relevant experience in biopharma, latest as CEO of Prosensa in The Netherlands, a company focusing on rare diseases, which was listed on NASDAQ in June 2013 and acquired by BioMarin early 2015. Mr. Schikan’s previous assignments include leadership roles at Genzyme (acquired by Sanofi) and Organon (acquired by Schering Plough). He previously served on the boards of Hansa Medical and Wilson Therapeutics (acquired by Alexion).

Other assignments: Chairman of the Board of Directors of Asceneuron, Switzerland, Interna, The Netherlands and Complix, Belgium. Member of the Board of Directors of Therachon, Switzerland, Swedish Orphan Biovitrum, Sweden, as well as of the Dutch Top Sector Life Sciences & Health, The Netherlands. Advisor to various organisations in Life Sciences & Health

.

 

Peter Ström

Maarten Kraan
Board Member

Maarten is the head of R&D at Pierre Fabre S.A. He brings more than 25 years of experience working as both academic and industry leader in scientific research across many therapeutics areas. Dr. Kraan has worked at the large pharmaceutical companies ScheringPlough, Bristol Myers Squibb, Roche/Genentech and AstraZeneca, and a venture funding backed Biotech start-up companies.

Other board assignments:  Toleranza AB

Göran Wessman

Sara Malcus
Board Member

Sara is the CEO of MetaboGen AB, a company developing products based on the human microbiome. Sara has a PhD in Inflammation medicine and extensive experience from early life science development in her previous role as Business Development and Investment Manager at GU Ventures AB. Over the past 8 years, she has held several executive positions in start-up companies, primarily focusing on pharmaceutical development. Before joining MetaboGen, Sara was part of the AstraZeneca global partnering team.

Other assignments: None

 

Scientific Advisors

Thomas Unger

Thomas Unger

M.D., Ph.D. and Professor in Pharmacology

Professor Thomas Unger is the Scientific Director at CARIM (School for Cardiovascular Diseases) at Maastricht University in Germany. He is a world-renowned researcher and authority in the cardiovascular area, with more than 600 published articles. He has taken a special interest in research on the AT 2 receptor. Prof. Unger is also a valued speaker at international conferences in the cardiovascular area and holds important positions in international scientific organizations.

 

Colin Sumners

Colin Sumners

Ph.D. and Professor in Physiology

Professor Colin Sumners, located at the University of Florida in Gainesville, USA, has studied the Renin Angiotensin System for ~40 years. He has extensive experience with regard to angiotensin actions in neural tissues and has published extensively in this area. His current focus is on the protective AT2 receptor in the brain, as a target for stroke- and anti-hypertensive therapeutics.

Maarten Kraan

MD, Ph.D., Adjunct Professor of Experimental Rheumatology

Maarten is the head of R&D at Pierre Fabre S.A. He brings more than 25 years of experience working as both academic and industry leader in scientific research across many therapeutics areas. Dr. Kraan has worked at the large pharmaceutical companies ScheringPlough, Bristol Myers Squibb, Roche/Genentech and AstraZeneca, and a venture funding backed Biotech start-up companies.